
In 1491, during his search for the Apple of Eden, stolen by Girolamo Savonarola,[a] Ezio Auditore da Firenze is summoned by his ally Antonio de Magianis to Venice to meet one of his contacts from Spain, Luis de Santángel. Representing the navigator Christopher Columbus, Luis asks Ezio to ensure the former's protection, fearing that someone is trying to assassinate him. Though initially reluctant, Ezio agrees to help after learning of Columbus's connections with the Templar grandmaster, Rodrigo Borgia. After foiling an attempt on Columbus's life, Ezio escorts him back to Luis, whereupon the two ask Ezio for a final favor: to recover an atlas from their hostel, which contains maps that detail travelling routes vital for their upcoming expedition. Ezio retrieves the atlas and brings it to Luis, who before leaving, reveals that most of the Spanish Assassin Brotherhood has been arrested by Tomás de Torquemada as part of the Spanish Inquisition.